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A movie showing how nuclear receptor changes its conformation in response to the ligand, referred to as "Mouse Trap".

FusionQuant, an algorithm that simultaneously detects and quantifies leukemia fusion genes and isoforms from RNA-Seq data in AML

INTRODUCTION The earliest fusion gene discovered in the history of biomedical science is one between the BCR gene and the ABL gene. This gene encodes the fusion protein known as BCR-ABL, which plays an important role in the development of t(9;22) chronic myeloid leukemia (CML).

Exploring the relationship between gene expression and leukemia prognosis in Shiny

The acute myeloid leukemia (AML) is one of the most devastating forms of cancer. AML prognosis is determined by many factors. Here, we build a dynamic application in Shiny to explore the relationship between patient prognosis and gene expression.